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莫秀梅


莫秀梅教授

莫秀梅,196112月生。生物材料与组织工程学科教授、博士生导师。本科和硕士毕业于华东理工大学,博士毕业于东华大学,1991-1997年为华东理工大学材料科学院副教授,1997-1999年为日本京都大学再生医科学研究所博士后,1999-2003年为新加坡国立大学生物医学工程研究员,2003-2004年为德国亚琛工业应用技术大学访问教授,200410月海外引进为东华大学教授,在东华大学组建了生物材料与组织工程研究室,开展静电纺纳米纤维仿生组织细胞外基质用于组织再生的研究,主持完成了科技部863,上海市科委重大基础研究子课题,国家自然科学基金,上海市浦江人才计划,纳米专项和国际合作项目等30项科研课题。发表文章300多篇,申请专利87项,授权27项。在纳米纤维用于血管再生、皮肤再生、神经再生、肌腱再生和软骨再生中做出了许多成果,ISI Web of Science显示她在静电纺丝领域的研究论文发表世界排名第七。研究成果分别荣获2008年上海市技术发明一等奖,2009年国家科技进步二等奖,2015年上海市自然科学三等奖。目前还开设了医用水凝胶做止血剂和粘合剂以及三维打印组织工程支架的研究方向。现担任中国复合材料学会超细纤维分会副主任委员,中国生物材料学会理事,中国生物医学工程协会生物材料分会理事,为“Frontiers of Materials Science ”国际刊物编委。

研究方向:

生物材料,纳米纤维,组织工程,再生医学。

1.静电纺纳米纤维在生物医学中的应用,包括小血管、神经、皮肤、骨和软骨等组织的再生,药物及活性物质的缓释

2.新型生物材料的研究开发,包括医用水凝胶,可降解聚合物的合成及应用研究

3.三维快速成型制备组织工程支架及在骨和软骨再生中的应用

主要研究成果:

1.制备出蛋白-多糖双组份医用胶粘合剂

2.制备出蛋白-多糖复合纳米纤维并成功地用于大鼠的皮肤缺损修复

3.制备出丝素-P(LLA-CL)复合纳米纤维导管并成功地用于大鼠的坐骨神经修复

4.制备出胶原蛋白-壳聚糖-P(LLA-CL)复合纳米纤维管状支架并成功地用于狗的股动脉缺损的修复

5. 制备出胶原蛋白-P(LLA-CL)取向多孔纳米纱,并成功地用于兔髌键的再生

6. 制备出明胶-PLA三维多孔纳米纤维支架,并成功地用于兔髌骨软骨再生

7. 制备出丝素-PLA三维多孔纳米纤维支架,并成功地用于大鼠颅骨再生

荣誉及获奖情况:

1.首届浦江人才

2.2008桑麻科教奖

3.2008上海市技术发明一等奖“水溶性医用几丁糖的制备技术及应用”

4.2009国家科技进步二等奖“水溶性几丁糖医用制品的研制及临床应用”

5.2009-2010年度东华大学“三八”红旗手

6.2010年上海市比翼双飞模范佳侣

7.2013年上海市巾帼建功标兵

8. 013-2014年度上海市教育系统三八红旗手

9. 20156月荣获第四批烟台高新区引进的“蓝海英才计划”高端创新人才称号

10.2015年作为第一完成人获得上海市自然科学三等奖, “静电纺纳米纤维用于组织再生”。

11.2016822日,荣获第六届“中国侨界贡献(创新人才)奖”


近几年主持的科研项目:

1.国家自然科学基金:甲壳素的结构性能及应用研究

2.国家自然科学基金:PEG接枝壳聚糖的备及性能研究

3.国家自然科学基金: 胶原蛋白-甲壳胺复合纳米纤维仿生组织细胞间质及与细胞相互作用的研究

4.国家自然科学基金:小口径血管的体内再生研究

5.国家自然科学基金:“双层仿生抗凝血血管支架及体内血管再生的研究”

6. 国家自然科学基金:“双营养因子缓释型轴向取向纳米纤维神经导管诱导长距离神经再生的研究”

7.国家自然科学基金:“仿生活性丝素蛋白-P(LLA-CL)微纳米纱线针织支架用于兔跟腱再生”

8.国家高技术研究发展863计划纳米材料与器件专题:蛋白-多糖复合纳米纤维用于组织修复的研究

9.教育部归国留学人员基金: 纳米纤维的制备表征及在组织工程中的应用开发

10.上海市2005年重大基础研究课题子课题: 组织工程相关生物材料的基础科学问题研究 中的小血管组织工程再建

11.上海市白玉兰科技人才基金:小口径血管组织再生的研究

12.上海市科委非政府国际合作项目: 控释型活性纳米纤维神经导管及心脏瓣膜的研制

13.上海市科纳米专项:纳米纤维仿生材料用于组织修复的研究

14. 上海市科纳米专项:蛋白-多糖-PLLA-CL)复合纳米纤维用于小血管组织再生

15. 上海市科委重点基础研究项目:“纳米纤维和纳米纱双层仿生血管支架及体内血管再生的研究”

16.上海市科委2015年科技支撑医疗器械项目:“活性纳米纤维神经导管的制备及体内神经再生的研究”

17.教育部博士点基金:“仿生活性纳米纤维神经导管诱导长距离神经再生的研究”

18. “纺织之光”应用基础研究项目, “活性纳米纤维神经导管用于长距离神经修复的研究 ”


近三年发表的论文:

1.Jing Wang, Lingling Tian, Nuan Chen, Seeram Ramakrishna, Xiumei Mo*The cellular response of nerve cells on poly-L-lysine coated PLGA-MWCNTs aligned nanofibers under electrical stimulationMaterials Science & Engineering C2018, 91, 715–726

2.Atta urRehman Khan, Shi Xiangyang, Aftab Ahmad and Xiu-mei Mo*Electrospinning of Crude Plant Extracts for Antibacterial and Wound Healing Applications: A ReviewSM Journal of Biomedical Engineering2018; 4(1): 1024

3.Kaile Zhang, Nailong Cao, XuranGuo, Qingsong Zou, Shukui Zhou, Ranxing Yang, Weixin Zhao, Xiumei Mo, Wei Liu, Qiang Fu*, The fabrication of 3D surface scaffold of collagen/poly (L-lactide-co-caprolactone) with dynamic liquid system and its application in urinary incontinence treatment as tissue engineered sub-urethral sling:In vitro and in vivostudy, NeurourologyandUrodynamics.2018;37:978985.

4.Weiming Chen, Hany El-Hamshary, Salem S. AL-Deyab, Xiumei Mo*, A method to control curcumin release from PELA fiber by heat treatment, Advances in Polymer Technology, 2018, 37(3), 21705

5.Wenshuai Fan, Jinghuan Li, Liu Yuan, Jifei Chen, Zhe Wang, Yiming Wang, ChanganGuo, Xiumei Mo, and Zuoqin Yan*, Intra-articular injection of kartogenin-conjugated polyurethane nanoparticles attenuates the progression of osteoarthritis, DRUG DELIVERY, 2018, 25(1), 1004–1012, https://doi.org/10.1080/10717544.2018.1461279

6.HaizhuKuang, Yao Wang, Junfeng Hu, Chunsheng Wang, Shuyang Lu, Xiumei Mo, A method for preparation of an internal layer of artificial vascular graft Co-modified with salvianolic acid B and heparin, ACS Applied Materials & Interfaces, 2018, 10(23), 19365-19372

7.Jing Wang, Lingling Tian, Liumin He, Nuan Chen, Seeram Ramakrishna, Kwok-Fai So, Xiumei Mo*, Lyciumbarbarum polysaccharide encapsulated Poly lactic-co-glycolic acid Nanofbers: cost efective herbal medicine for potential application in peripheral nerve tissue engineeringScientific Reports, (2018) 8:8669, DOI:10.1038/s41598-018-26837-Z

8.Jing Wang, Lingling Tian, Baiwen Luo, Seeram Ramakrishna, Dan Kai*, Xian Jun Loh, In Hong Yang, G. Roshan Deen, Xiumei Mo*Engineering PCL/Lignin Nanofibers as an Antioxidant Scaffold for the Growth of Neuron and Schwann cellColloids and Surfaces B: Biointerfaces2018, 169, 356-365

9.Jun Ma, Yunfei He, Xilin Liu, Weiming Chen, An Wang, Chia-Ying Lin, Xiumei Mo, Xiaojian Ye, Anovelelectrospun-aligned nanoyarn/three-dimensional porous nanofibrous hybrid scaffold for annulus fibrosus tissue engineering, International Journal of Nanomedicine, 2018:13 1553–1567

10.Wencheng Liang, JiaHou, Xiangchen Fang, Fudong Bai, Tonghe Zhu, Feifei Gao, Chao Wei, Xiumei Mo, Meidong Lang, Syntheses of cellulose diacetate based copolymer electrospun nanofibers for tissue scaffold, Applied surface Science, 2018, 443, 374-381

11.Tong Wu, JiajiaXue, Haoxuan Li, Chunlei Zhu, Xiumei Mo, and Younan Xia*, General Method for Generating Circular Gradients of Active Proteins on Nanofiber Scaffolds Sought for Wound Closure and Related Applications, ACS Applied Materials & Interfaces, 2018, 10, 8536−8545

12.Xiaojun Zhou, WeizongWeng, Bo Chen, Wei Feng, Weizhong Wang, Wei Nie, Liang Chen, Xiumei Mo, Jiacan Su *, Chuanglong He *, Mesoporous silica nanoparticles/gelatin porous composite scaffolds with localized and sustained release of vancomycin for treatment of infected bone defects, Journal of Materials Chemistry B, 2018,6,740-752

13.Liu YUAN, Wenshuai FAN, Linyingjun HAN, Changan GUO, Zuoqin YAN, Meifang ZHU, and Xiumei MO*Evaluation of hydrogels for soft tissue adhesives in vitro and in vivo analysesFront. Mater. Sci. 2018, 12(1): 95–104

14.Tong Wu, Jialing Zhang, Yuanfei Wang, Dandan Li, Binbin Sun, Hany El-Hamshary, Meng Yin*, Xiumei Mo*Fabrication and preliminary study of a biomimetic tri-layer tubular graft based on fibers and fiber yarns for vascular tissue engineeringMaterials Science & Engineering C201882, 121–129

15.Zhiwen Zeng, Hongsheng Wang, YosryMorsi, Xiumei Mo*, Synthesis and characterization of incorporating mussel mimetic moieties into photoactive hydrogel adhesive, Colloids and Surfaces B: Biointerfaces, 2018, 161, 94–102

16.ZiqiGu, Haiyue Yin, Juan Wang, Linlin Ma, YosryMorsi, Xiumei Mo*, Fabrication and characterization of TGF-1-loaded electrospun poly (lactic-co-glycolic acid) core-sheath sutures,Colloids and Surfaces B: Biointerfaces 2018, 161, 331–338

17.SUN Binbin( 孙彬彬) WU Tong( 吴桐) WANG Juan( 王娟) BHUTTO M Aqeel( 布托阿齐) YUAN Liu( 袁柳) LI Dandan( 李丹丹) MO Xiumei( 莫秀梅) *Fabrication and Characterization of Dual-layer Multichannel Nerve Guidance ConduitJournal of Donghua University ( Eng. Ed.) 2017, 34(1), 167-170

18.Jing Wang, Nuan Chen, Seeram Ramakrishna, LinglingTian,* and Xiumei Mo*, The Effect of Plasma Treated PLGA/MWCNTs-COOH Composite Nanofibers on Nerve Cell Behavior, Polymer 2017, 9, 713

19.Kui Yu, Xiangxiang Zhou, EI-Assar M R, Tonghe Zhu, Yu Wu, Juang Wang, Wenhao Feng, YosryMorsi, Xiumei MO*, Preparation and Characterization of Chitosan Nanofibers Containing Silver Nanoparticles, Journal of Donghua University (Eng. Ed.) , 2017,34(1) 105-110

20.Xiaojun Zhou, Ming Qin, Liang Chen, Wei Nie, Xiumei Mo, Chuanglong He*, Effect of Polyethlenimine Content on Liposome/Polyethylenimine Complexes Mediated Gene Delivery, Journal of Donghua University (Eng. Ed.) , 2017, 34(2) 195-198

21.蔡江瑜,蒋佳,莫秀梅,陈世益,丝素蛋白/聚乳酸-聚己内酯纳米纤维支架对兔腱-骨愈合影响的实验,中国修复重建外科杂志,2017, 318),957-962

22.Fengjuan Zou, Runrun Lia, Jianjun Jiang, Xiumei Mo, Guofeng Gu, Zhongwu Guo and Zonggang ChenMechanical enhancement and in vitro biocompatibility of nanofibrous collagen-chitosan scaffolds for tissue engineeringJournal of Biomaterials Science, Polymer Edition, 201728(18), 2255–2270

23.Anlin Yin, Jiukai Li, Xiumei Mo, Rifang Luo, Xingdong Zhang, Yunbing Wang, Fabrication and characteration of coaxial electrospun multicomponent fibrous graft for vascular tissue engineering, Journal of Controlled Release, 2017, 259, e5–e195

24.Tong Wu, Binbin Sun, Dandan Li, Xiumei MoAnti-CD133 antibody loaded bilayer tubular scaffold based on poly(L-lactide-co-caprolactone)/collagen nanofibers and nanoyarns for vascular tissue engineering, Journal of Controlled Release, 2017, 259, e5–e195

25.Linpeng Fan, ZengxiaoCai, XiaohuaGeng, Hongsheng Wang⁎⁎, Jingliang Li, Chuanglong He, Xiumei Mo, Xungai Wang, Fabrication and characterization of compound vitamin B/silk fibroin nanofibrous matrices, Journal of Controlled Release 2017, 259, e5–e195

26.Chongyang Wang, WenxiuHou, XuranGuo, Juehong Li, Tu Hu, ManleQiu, Shen Liu, Xiumei Mo, Xudong Liu, Two-phase electrospinning to incorporate growth factors loaded chitosan nanoparticles into electrospun fibrous scaffolds for bioactivity retention and cartilage regeneration, Materials Science and Engineering C, 2017,79, 507–515

27.Tian Zhou, Xin Liu, Baiyan Sui, Chao Liu, Xiumei Mo* and Jiao Sun*, Development of fish collagen/bioactive glass/chitosan composite nanofibers as a GTR/GBR membrane for inducing periodontal tissue regeneration, Biomed. Mater. 2017, 12, 055004

28.Zhiwen Zeng, Xiumei Mo*, Rapid in situ cross-linking of hydrogel adhesives based on thiol-grafted bioinspired catechol-conjugated chitosan, Journal of Biomaterials Applications 2017, 32(5), 612–621

29.Kaile Zhang, Nailong Cao, XuranGuo, Qingsong Zou, Shukui Zhou, Ranxing Yang, Weixin Zhao, Xiumei Mo, Wei Liu, Qiang Fu, The fabrication of 3D surface scaffold of collagen/poly(L-lactide-co-caprolactone) with dynamic liquid system and its application in urinary incontinence treatment as a tissue engineered sub-urethral sling: In vitro and in vivo study, Neurourology and Urodynamics, 2017, 1-8

30.Juan WANG, Binbin SUN, Muhammad Aqeel BHUTTO, Tonghe ZHU, Kui YU, Jiayu BAO, Yosry MORSI, Hany EL-HAMSHARY, Mohamed EL-NEWEHY, and Xiumei MO*Fabrication and characterization of Antheraeapernyi silk fibroin-blended P(LLA-CL) nanofibrous scaffolds for peripheral nerve tissue engineering, Front. Mater. Sci. 2017, 11(1): 22–32

31.AbdallaAbdal-hay, Adnan Memic, Kamal H. Hussein, Yi Seul Oh, Mohamed Fouad, Fawzi F. Al-Jassir, Heung-Myong Woo, YosryMorsi, Xiumei Mo, SašoIvanovski*, Rapid fabrication of highly porous and biocompatible composite textile tubular scaffold for vascular tissue engineering, European Polymer Journal, 2017, 96, 27-43

32.Yu WU, Liu YUAN, Nai-an SHENG, Zi-qi GU, Wen-hao FENG, Hai-yue YIN, Yosry MORSI, and Xiu-mei MO*A soft tissue adhesive based on aldehyde-sodium alginate and amino-carboxymethyl chitosan preparation through the Schiff reactionFront. Mater. Sci. 2017, 11(3): 215–222

33.Wenhao Feng, Peixi Liu, Haiyue Yin, ZiqiGu, Yu Wu, Wei Zhu, Yingjun Liu, Hao Zheng and Xiumei MO*, Heparin and rosuvastatin calcium-loaded poly-( L -lactide-co-caprolactone) nanofiber-covered stent-grafts for aneurysm treatment, New J.Chem., 2017, 41, 9014-9023, impact factor 3.269

34.Haiyue Yin, Juan Wang, ZiqiGu, Wenhao Feng, Manchen Gao, Yu Wu, Hao Zheng, Xiaomin He and Xiumei Mo*, Evaluation of the potential of kartogenin encapsulated poly(L-lactic acid-co-caprolactone)/collagen nanofibers for tracheal cartilage regeneration, Journal of Biomaterials Applications, 2017, 32(3) , 331–341, imnpact factor 2.3

35.Binbin Sun, Zifei Zhou, Tong Wu, Weiming Chen, Dawei Li, Hao Zheng, Hany El-Hamshary, Salem S. Al-Deyab4, Xiumei Mo*, Yinxian Yu*, Development of Nanofiber Sponges-Containing Nerve Guidance Conduit for Peripheral Nerve Regeneration in Vivo, ACS Applied Materials & Interfaces, 2017, 9, 26684−26696

36.PiJun Yu, JiAnGuo, JunJie Li, Xiao Shi, LuPing Wang, Wei Chen, and XiuMei MoRepair of Skin Defects with Electrospun Collagen/Chitosan and Fibroin/Chitosan Compound Nanofiber Scaffolds Compared with Gauze Dressing,Journal of Biomaterials and Tissue Engineering, 2017, 7(5), 386-392

37.Yinxian YU, Binbin SUN, Chengqing YI, and Xiumei MO*, Stem cell homing-based tissue engineering using bioactive materials, Front. Mater. Sci. 2017, 11(2): 93–105

38.Jing Wang, Binbin Sun, Lingling Tian, Xiaomin He, Qiang Gao, Tong Wu, Seeram Ramakrishna, Jinghao Zheng, Xiumei Mo*, Evaluation of the potential of rhTGF- β3 encapsulated P(LLA-CL)/collagen nanofibers for tracheal cartilage regeneration using mesenchymal stems cells derived from Wharton's jelly of human umbilical cord, Materials Science and Engineering C 70 (2017) 637–645

39.Bensong Han, Feng Xue, Cunyi Fan and Xiumei Mo, Surface heparinization and blood compatibility modification of small intestinal submucosa (SIS) for small-caliber vascular regeneration, Bio-Medical Materials and Engineering 2017, 28, 213–222

40.Liu Yuan, Yu Wu, Jun Fang, Xiaojuan Wei, QishengGu, Hany El-Hamshary, Salem S. Al-Deyab, YosryMorsi&Xiumei Mo*, Modified alginate and gelatin cross-linked hydrogels for soft tissue adhesive, Artificial Cells, Nanomedicine, and Biotechnology An International Journal, 2017, 45(1),76-83, impact factor 5.605

41.Liu Yuan, Yu Wu, Qi-sheng Gu, Hany El-Hamshary, Mohamed El-Newehy, Xiumei Mo, Injectable photo crosslinked enhanced double-network hydrogels from modified sodium alginate and gelatin, International Journal of Biological Macromolecules, 2017, 96, 569–577

42.Kaile Zhang, Qiang Fu, James Yoo, Xiangxian Chen, Prafulla Chandra, Xiumei Mo, Lujie Song, Anthony Atala, Weixin Zhao*, 3D bioprinting of urethra with PCL/PLCL blend and dual autologous cells in fibrin hydrogel: An in vitro evaluation of biomimetic mechanical property and cell growth environment, ActaBiomaterialia 2017, 50, 154–164

43.YiboGan, Pei Li, Liyuan Wang, Xiumei Mo, Lei Song, Yuan Xu, Chen Zhao, Bin Ouyang, Bing Tu, Lei Luo, Linyong Zhu, Shiwu Dong, Fuyou Li, Qiang Zhou, An interpenetrating network-strengthened and toughened hydrogel that supports cell-based nucleus pulposus regeneration, Biomaterials 2017, 136 , 12-28

44.Tonghe Zhu, Kui Yu, M. Aqeel Bhutto, XuranGuo, Wei Shen, Juan Wang, Weiming Chen, Hany El-Hamshary, Salem S. Al-Deyab, Xiumei Mo*Synthesis of RGD-peptide modified poly(ester-urethane) urea electrospun nanofibers as a potential application for vascular tissue engineering, Chemical Engineering Journal 2017, 315, 177–190, Impact factor 6.1206

45.Tong Wu, Jialing Zhang, Yuanfei Wang, Binbin Sun, XuranGuo, YosryMorsi, Hany El-Hamshary, Mohamed El-Newehy, and Xiumei Mo*, Development of Dynamic Liquid and Conjugated Electrospun Poly(L-lactide-co-caprolactone)/Collagen Nanoyarns for Regulating Vascular Smooth Muscle Cells Growth, Journal of Biomedical Nanotechnology, 2017, 13, 303–312

46.Tian Zhou, Baiyan Sui, Xiumei Mo*, Jiao Sun*, Multifunctional and biomimetic fish collagen/bioactive glass nanofibers: fabrication, antibacterial activity and inducing skin regeneration in vitro and in vivo, International Journal of Nanomedicine 2017:12 3495–3507

47.Tong Wu, Dandan Li,Yuanfei Wang,Binbin Sun,Dawei Li,YosryMorsi, Hany El-Hamshary,Salem S. Al-Deyaband Xiumei Mo*, Laminin-coated nerve guidance conduits based on poly(L-lactide-co-glycolide) fibers and yarns for promoting Schwann cells’ proliferation and Migration, J. Mater. Chem. B,2017, 5, 3186—3194

48.Weiming Chen, Binbin Sun, Tonghe Zhu, Qiang Gao, YosryMorsi, Hany El-Hamshary,Mohamed El-Newehy, Xiumei Mo, Groove fibers based porous scaffold for cartilage tissue engineering application, Materials Letters 2017, 192, 44–47

49.Anlin Yin*, Rifang Luo, Jiukai Li, Xiumei Mo*, Yunbing Wang*, XingdongZhang,Coaxialelectrospinning multicomponent functional controlled-release vascular graft: Optimization of graft propertiesColloids and Surfaces B: Biointerfaces 2017, 152, 432–439

50.Kui Yu, TongheZhu,Yu Wu, Xiangxiang Zhou, Xingxing Yang, Juan Wang, Jun Fang, Hany El-Hamshary, Salem S. Al-Deyab, Xiumei Mo*, Incorporation of amoxicillin-loaded organic montmorillonite into poly(ester-urethane) urea nanofibers as a functional tissue engineering scaffold, Colloids and Surfaces B: Biointerfaces, 2017, 151,314–323

51.Tong Wu,Hui Zheng,Jianfeng Chen,Yuanfei Wang,BinbinSun,YosryMorsi,Hany El-Hamshary,Salem S. Al-Deyab,Chang Chen*and Xiumei Mo*Application of a bilayer tubular scaffold based on electrospun poly(L-lactide-co-caprolactone)/collagen fibers and yarns for tracheal tissue engineering, Journal of Materials Chemistry B, 2017, 5,139-150

52.Sun, Binbin; Wu, Tong; He, Liping; Zhang, Jianguang; Yuan, Yuyu; Huang, Xijun; EI-Hamshary, Hany; Al-Deyab, Salem S.; Xu, Tao*; Mo, Xiumei*, Development of Dual Neurotrophins-Encapsulated ElectrospunNanofibrous Scaffolds for Peripheral Nerve Regeneration, Journal of Biomedical Nanotechnology, 2016,12(11), 1987-2000

53.Gao, Qiang; Huang, Chao; Sun, Binbin; Aqeel, Bhutto M.; Wang, Jing; Chen, Weiming; Mo, Xiumei*; Wan, Xinjian*, Fabrication and characterization of metal stent coating with drug-loaded nanofiber film for gallstone dissolution, Journal of Biomaterials Applications, 2016, 31(5), 784-796

54.Yang, Xingxing; Wang, Xiaoyun; Yu, Fan; Ma, Linlin; Pan, Xiaohan; Luo, Gejie; Lin, Si; Mo, Xiumei; He, Chuanglong; Wang, Hongsheng*, Hyaluronic acid/EDC/NHS-crosslinked green electrospun silk fibroin nanofibrous scaffolds for tissue engineering,Rsc Advances, 2016, 6(102),99720-99728

55.Gan, Yibo; Li, Sukai; Li, Pei; Xu, Yuan; Wang, Liyuan; Zhao, Chen; Ouyang, Bin; Tu, Bing; Zhang, Chengmin; Luo, Lei; Luo, Xiangdong; Mo, Xiumei*; Zhou, Qiang*, A Controlled Release Codelivery System of MSCs Encapsulated in Dextran/Gelatin Hydrogel with TGF-beta 3-Loaded Nanoparticles for Nucleus Pulposus Regeneration, Stem Cells International, 2016, Article ID 9042019, 14 pages, http://dx.doi.org/10.1155/2016/9042019

56.Dapeng Fan, Shen Liu, Shichao Jiang, Zhiwei Li, Xiumei Mo,HongjiangRuan, Gang-Ming Zou,* Cunyi Fan, The use of SHP-2 gene transduced bone marrow mesenchymal stem cells to promote osteogenic differentiation and bone defect repair in rat Journal of Biomedical Materials Research Part A, 2016104(8), 1871-1881

57.Binbin Sun,Tong Wu,Juan Wang,Dawei Li,Jing Wang,Qiang Gao, M. Aqeel Bhutto,Hany El-Hamshary,Salem S. Al-Deyabcand Xiumei Mo*, Polypyrrole-Coated Poly(l-lactic acid-co-ε-caprolactone)/Silk Fibroin Nanofibrous Membranes Promoting Neural Cells Proliferation and Differentiation with Electrical Stimulation. Journal of Materials Chemistry B, 2016. 4, 6670-6679

58.Jialin Song, Binbin Sun, Shen Liu, Wei Chen, Yuanzheng Zhang, Chunyang Wang, Xiumei Mo, JunyiChe, Yuanming Ouyang, Weien Yuan and Cunyi FanPolymerizing Pyrrole Coated Poly (l-lactic acid-co-+-caprolactone) (PLCL) Conductive Nanofibrous Conduit Combined with Electric Stimulation for Long-Range Peripheral Nerve RegenerationFrontiers in Molecular Neuroscience, 2016, 9 , 117, www.frontiersin.org

59.Anlin Yin, Gary L. Bowlin, Rifang Luo, XingdongZhang,Yunbing Wang*, and Xiumei Mo*, Electrospun silk fibroin/poly (L-lactide-ecaplacton) graft with platelet-rich growth factor for inducing smooth muscle cell growth and infiltrationRegenerative Biomaterials, 2016, 239–245doi: 10.1093/rb/rbw026

60.Juan Wang, Zhuping Yin, Xiang Xue, Subhas C. Kundu, Xiumei Moand Shenzhou Lu, Natural Non-Mulberry Silk Nanoparticles for Potential-Controlled Drug Release, Int. J. Mol. Sci.2016,17(12), 2012; doi:10.3390/ijms17122012

61.Kui Yu, Xiangxiang Zhou, Tonghe Zhu, Tong Wu, Juan Wang, Jun Fang, M. R. El-Aassar, Hany El-Hamshary, Mohamed El-Newehy and Xiumei Mo*. Fabrication of poly(ester-urethane) urea elastomer/gelatin electrospunnanofibrous membranes for the potential application in skin tissue engineering.RSC Advances, 2016, 6(77): 73636-73644.

62.Xiaojun Zhou,Liang Chen,Wei Nie,Weizhong Wang,Ming Qin,Xiumei Mo, Hongsheng Wang,and Chuanglong He, Dual-Responsive Mesoporous Silica Nanoparticles Mediated Codelivery of Doxorubicin and Bcl2 SiRNA for Targeted Treatment of Breast Cancer, The Journal of Physical Chemistry, C 2016, 120, 22375−22387

63.XuranGuo, Kaile Zhang, Mohamed El-Aassar, Nanping Wang, Hany El-Hamshary, Mohamed El-Newehy, Qiang Fu , And Xiumei Mo* The comparison of the Wnt signaling pathway inhibitor delivered electrospunnanoyarn fabricated with two methods for the application of urethroplastyFront. Mater. Sci. 2016, 10(4): 346–357

64.郭煦然,张楷乐,朱同贺,莫秀梅*。基于静电纺丝技术的纳米纱纳米纤维膜的三维多孔支架的制备及性能研究[J]。中国科技论文在线精品论文。20169月第9卷第17期。CN11-9150/N5;ISSN1674-2850

65.Jun Fang,Jialing Zhang,Jun Du,Yanjun Pan,Jing Shi,Yongxuan Peng,Weiming Chen, Liu Yuan,Sang-Ho Ye,William R. Wagner,MengYin,*and Xiumei Mo*Orthogonally Functionalizable Polyurethane with Subsequent Modification with Heparin and Endothelium-Inducing Peptide Aiming for Vascular ReconstructionACS Applied Materials &Interfaces, 2016, 8, 14442-14452

66.Weiming Chen, Shuai Chen, YosryMorsi, Hany El-Hamshary, Mohamed El-Newhy, CunyiFan,* and Xiumei Mo*, Superabsorbent 3D Scaffold Based on Electrospun Nanofibers for Cartilage Tissue Engineering, ACS Applied Materials &Interfaces, 2016, 8, 24415-24425

67.Jialing Zhang, Jun Du, Dekai Xia, Jinlong Liu, Tong Wu, Jing Shi, Wei Song, DaweiJin, Xiumei Mo*, and Meng Yin*, Preliminary study of a novel nanofiber-based valve integrated tubular graft as an alternative for a pulmonary valved artery, RSC Advance., 2016, 6, 84837–84846

68.KexinQiu, Bo Chen, Wei Nie, Xiaojun Zhou, Wei Feng, Weizhong Wang, Liang Chen, Xiumei Mo, Youzhen Wei, and Chuanglong He, Electrophoretic Deposition of Dexamethasone-Loaded Mesoporous Silica Nanoparticles onto Poly(L‑Lactic Acid)/Poly(ε-Caprolactone) Composite Scaffold for Bone Tissue Engineering, ACS Applied Materials &Interfaces, 2016, 8, 4137-4148

69.Dawei Li, Weiming Chen, Binbin Sun, Haoxuan Li, Tong Wu, QinfeiKe, Chen Huang, Hany EI-Hamshary, Salem S. Al-Deyab, Xiumei Mo*, A comparison of nanoscale and multiscale PCL/gelatin scaffolds prepared by disc-electrospinning, Colloids and Surfaces B: Biointerfaces 2016,146, 632–641

70.M. R. El-Aassar, Xiumei Mo*, Development of porous alginate microbeads containing silver nanoparticles and their antibacterial efficacy, Advances in Polymer Technology, 2016,35 (3) 298-306

71.M.R. El-Aassar, G F El Fawal, Nehal M. El-Deeb, H. Shokry Hassan, Xiumei Mo*, Electrospun polyvinyl alcohol/ Pluronic F127 blended nanofibers containing titanium dioxide for antibacterial wound dressing, Applied Biochemistry and Biotechnology, 2016,178 (8), 1488-1502

72.高强,黄超,孙彬彬,陈维明,王静,宛新建,莫秀梅*, 一种治疗胆总管结石新型药物洗脱复合金属支架的制备及表征,中国科技论文在线,2016, [2016-09-29]. http://www.paper.edu.cn

73.Zhiwen Zeng,Xiu-mei Mo*,Chuanglong He,YosryMorsi,Hany El-Hamshary and Mohamed El-Newehy, An in situ forming tissue adhesive based on poly(ethylene glycol)-dimethacrylate and thiolated chitosan through the Michael reaction, Journal of Materials Chemistry B, 2016, 4, 5585-5592

74.Bhutto M. Aqeel, Tong Wu, Binbin Sun, Hany EI-Hamshary, Salem S. Al-Deyab, Xiumei Mo*, Fabrication and Characterization of Vitamin B5 loaded Poly (L-lactide-cocaprolactone)/ Silk fiber Aligned Electrospun Nanofibers for Schwann cell proliferation, Colloids and Surfaces B: Biointerfaces2016, 144, 108-117

75.Kaile Zhang, XuranGuo, Yan Li, Qiang Fu, Xiumei Mo*, Kyle Nelson,Weixin Zhao, Electrospunnanoyarn seeded with myoblasts induced from placentalstem cells for the application of stress urinary incontinence sling: Anin vitro study, Colloids and Surfaces B: Biointerfaces2016144, 21-32

76.Bhutto M. Aqeel and Xiumei Mo*, Fabrication and characterization of water soluble vitamin loaded Poly (lactic-co-glycolic acid) aligned electrospun nanofibers, International Journal of Research, 2016, 3(8), 348-355

77.Tonghe Zhu, Kui Yu, M. Aqeel Bhutto, Juan Wang, Wei Shen, Wei Song, Xiangxiang Zhou, Hany EI-Hamshary, Salem S. Al-Deyab, Xiumei Mo*, A facile approach to fabricate nano-attapulgite/poly(vinyl pyrrolidone)/biopolymers core-sheath ultrafine fibrous mats for drug controlled release, RSC Advances, 2016, 6, 49817–49823

78.Tian Zhou, Nanping Wang, Yang Xue, Tingting Ding, Xin Liu, Xiumei Mo*, and Jiao Sun, Electrospun tilapia collagen nanofibers accelerating wound healingvia inducing keratinocytes proliferation and differentiation, Colloids and Surfaces B: Biointerfaces, 2016, 143, 415–422

79.Jianchao Zhan, YosryMorsi, Hany EI-Hamshary, Salem S. Al-Deyab, Xiumei Mo*Preparation and Characterization of Electrospun in-situ Crosslinked Gelatin-Graphite Oxide  Nanofibers, Journal of Biomaterials Science, Polymer Edition, 2016, 27(5), 385-402.

80.Jiangchao Zhan, Junyi Liu, Cunyang Wang, Cunyi Fang, Hany A. EI-Hamshary, Salem S. Al-Deyab,Xiumei Mo*,Electrospun Silk Fibroin/Poly(lactic-co-glycolic acid) nanofibers for nerver tissue engineering, Journal of Bioactive and Compatible Polymer, 2016, 31(2), 208-224.

81.Weiming ChenJun Ma, Lei Zhu, YosryMorsi, Hany EI-Hamsharye, Salem S. Al-Deyabe, Xiumei Mo*Superelastic, superabsorbent and 3D nanofiber-assembled scaffold for tissue engineeringColloids and Surfaces B: Biointerfaces2016142165–172

82.M. Aqeel Bhutto, Jianguang Zhang, Binbin Sun, Hany El-Hamshary, Salem S. Al-Deyab, Xiumei Mo*, Development of poly (L-lactide-co-caprolactone) multichannel nerve conduit with aligned electrospun nanofibers for Schwann cell proliferation, International Journal Of Polymeric Materials And Polymeric Biomaterials, 201665(7), 323-329

83.Jianchao Zhan, YosryMorsi, Hany EI-Hamshary, Salem S. Al-Deyab, Xiumei Mo*, In vitro evaluation of electrospun gelatin–glutaraldehyde nanofibers, Front. Mater.Sci, 2016, 10 (1), 90-100

84.Xianyou Zheng, WeiWang, Shen Liu, Jinglei Wu, Fengfeng Li, Lei Cao, Xu-dong Liu, Xiumei Mo*, Cunyi Fan*, Enhancement of chondrogenic differentiation of rabbit mesenchymal stem cells by oriented nanofiber yarn-collagen type I/hyaluronate hybrid, Materials Science and Engineering C, 2016,58, 1071–1076


主要学术任职

1.中国生物材料学会理事

2.中国生物材料学会心血管材料分会委员

3.中国生物材料学会海洋生物材料分会理事

4.中国生物医学工程学会生物材料分会理事

5.中国复合材料学会超细纤维复合材料分会副主任委员

6.中国复合材料学生物医用复合材料分会委员

7.上海市生物医学工程学会理事

8.中国医药卫生文化协会生物医学材料专委会委员

9.Springer 的国际新刊物 “Frontiers of Materials Science” 的编委


国际交流与合作:

目前与新加坡国立大学(National University of Singapore),美国孟菲斯大学(UniversityofMemphis),澳大利亚斯文伯恩技术大学(Swinburne University of Technology),澳大利亚迪肯大学(Deakin University,沙特国王大学(King Saud University),英国伦敦学院大学(UCL有合作科研和教学,

联系电话:021-67792653                                                                            EMAILxmm@dhu.edu.cn