申杰峰  研究员

 

申杰峰,1979年生于江苏大丰。上海交通大学工学博士、博士后,Texas Tech University博士后,先后就职于上海交通大学药学院,东华大学化学化工学院现为东华大学化学与化工学院研究员博导先后主持、参加国家自然基金、重大专项以及产学研项目多项,主持和主要参与的科研项目经费共计4000余万元。先后发表sci论文20余篇,授权专利6项,获得上海市产学研合作优秀项目奖特等奖。

 




研究方向

1、 不对称催化研究及应用

2、 绿色新工艺研究及开发

3、 天然产物分离及合成

 

近年来承担的主要科研项目:

1、医药中间体、杀菌剂的新工艺开发(270万)             产学研合作(2023-2026

2、季戊四醇工艺产学研开发合作                           产学研合作(2022-2023

3手性双金属催化的不对称烯丙基串联反应立体发散性合成多手性杂环化合物的研究                                自然基金面上项目(2020-2023

4TGIC的新工艺及中试(600万)                         产学研合作(2020-2023

5RuPHOX–Ru催化的α,β-不饱和羰基化合物及青蒿酸的不对称氢化研究

自然基金青年基金(2014-2017

 

近年来发表的代表性论著、专利:

论文

1.K Xu, Jianxun Ye, Hao Liu, Jiefeng Shen*, Delong Liu*, Wanbin Zhang.  Pd-Catalyzed Asymmetric Allylic Substitution Annulation Using Enolizable Ketimines as Nucleophiles: An Alternative Approach to Chiral Tetrahydroindoles. Adv. Synth. Catal. 2020, 362, 2059-2069.

2.Jing Li, Yufei Lu, Yue Zhu,Yu Nie, Jiefeng Shen*, Yangang Liu, Delong Liu* ,and Wanbin Zhang. Selective Asymmetric Hydrogenation of Four-Membered Exo-alpha,beta-Unsaturated Cyclobutanones Using RuPHOX-Ru as a Catalyst. Org. Lett. 2019, 21, 4331-4335.

3.K Xu, Hao Liu, Yanlin Hou, Jiefeng Shen*, Delong Liu*, Wanbin Zhang. A Pd-catalyzed asymmetric allylic substitution cascade via an asymmetric desymmetrization for the synthesis of bicyclic dihydrofurans. Chem.Commun. 2019, 88, 13295-13298.

4.Yufei Lu, Jing Li, Yue Zhu, Jiefeng Sheng*, Delong Liu*, Wanbin Zhang. Synthesis of chiral gamma-lactones via a RuPHOX-Ru catalyzed asymmetric hydrogenation of aroylacrylic acids. Tetrahedron 2019, 75, 3643-3649.

5.Chenghao Ye, Xuezhen Kou, Guoqiang Yang, Jiefeng Shen*, and Wanbin Zhang*. PhI(OAc)2-mediated alkoxyoxygenation of beta,gamma-unsaturated ketoximes: Preparation of isoxazolines bearing two contiguous tetrasubstituted carbons. Tetrahedron Lett. 2019, 60, 1148-1152.

6.Kai Xu, Hao Liu, Delong Liu, Cheng Sheng, Jiefeng Shen*, and Wanbin Zhang*. Synthesis of (+)-salvianolic acid A from sodium Danshensu. Tetrahedron 2018, 74, 996-6002.

7.Jiangyan Jing, Xiaohong Huo, Jiefeng Shen*, Jingke Fu, Qinghua Meng, and Wanbin Zhang*. Direct use of allylic alcohols and allylic amines in palladium-catalyzed allylic amination. Chem. Commun. 2017, 53, 5151-5154.

 

E-MAILjiefeng@dhu.edu.cn