莫秀梅教授

莫秀梅,196112月生。生物材料与组织工程学科教授、博士生导师。本科和硕士毕业于华东理工大学,博士毕业于东华大学,1991-1997年为华东理工大学材料科学院副教授,1997-1999年为日本京都大学再生医科学研究所博士后,1999-2003年为新加坡国立大学生物医学工程研究员,2003-2004年为德国亚琛工业应用技术大学访问教授,自200410月海外引进为东华大学教授,在东华大学组建了生物材料与组织工程研究室,开展静电纺纳米纤维仿生组织细胞外基质用于组织再生的研究,主持完成了科技部863,上海市科委重大基础研究子课题,国家自然科学基金,上海市浦江人才计划,纳米专项和国际合作项目等30项科研课题。发表文章300多篇,申请专利87项,授权27项。在纳米纤维用于血管再生、皮肤再生、神经再生、肌腱再生和软骨再生中做出了许多成果,ISI Web of Science显示她在静电纺丝领域的研究论文发表世界排名第七。研究成果分别荣获2008年上海市技术发明一等奖,2009年国家科技进步二等奖 ,2015年上海市自然科学三等奖。目前还开设了医用水凝胶做止血剂和粘合剂以及三维打印组织工程支架的研究方向。现担任中国复合材料学会超细纤维分会副主任委员,中国生物材料学会理事,中国生物医学工程协会生物材料分会理事,为“Frontiers of Materials Science”国际刊物编委。

 研究方向:

生物材料,纳米纤维,组织工程,再生医学。

1.静电纺纳米纤维在生物医学中的应用,包括小血管、神经、皮肤、骨和软骨等组织的再生,药物及活性物质的缓释

2.新型生物材料的研究开发,包括医用水凝胶,可降解聚合物的合成及应用研究

3.三维快速成型制备组织工程支架及在骨和软骨再生中的应用

主要研究成果:

1.制备出蛋白-多糖双组份医用胶粘合剂

2.制备出蛋白-多糖复合纳米纤维并成功地用于大鼠的皮肤缺损修复

3.制备出丝素-P(LLA-CL)复合纳米纤维导管并成功地用于大鼠的坐骨神经修复

4.制备出胶原蛋白-壳聚糖-P(LLA-CL)复合纳米纤维管状支架并成功地用于狗的股动脉缺损的修复

5.制备出胶原蛋白-P(LLA-CL)取向多孔纳米纱,并成功地用于兔髌键的再生

6.制备出明胶-PLA三维多孔纳米纤维支架,并成功地用于兔髌骨软骨再生

7.制备出丝素-PLA三维多孔纳米纤维支架,并成功地用于大鼠颅骨再生

荣誉及获奖情况:

1.首届浦江人才

2.2008桑麻科教奖

3.2008上海市技术发明一等奖“水溶性医用几丁糖的制备技术及应用”

4.2009国家科技进步二等奖“水溶性几丁糖医用制品的研制及临床应用”

5.2009-2010年度东华大学“三八”红旗手

6.2010年上海市比翼双飞模范佳侣

7.2013年上海市巾帼建功标兵

8.2013-2014年度上海市教育系统三八红旗手

9.20156月荣获第四批烟台高新区引进的“蓝海英才计划”高端创新人才称号

10.2015年作为第一完成人获得上海市自然科学三等奖 ,  “静电纺纳米纤维用于组织再生”。

11.2016822日,荣获第六届“中国侨界贡献(创新人才)奖”

近几年主持的科研项目:

1.国家自然科学基金:甲壳素的结构性能及应用研究

2.国家自然科学基金:PEG接枝壳聚糖的备及性能研究

3.国家自然科学基金:  胶原蛋白-甲壳胺复合纳米纤维仿生组织细胞间质及与细胞相互作用的研究

4.国家自然科学基金:小口径血管的体内再生研究

5.国家自然科学基金:“双层仿生抗凝血血管支架及体内血管再生的研究”

6.国家自然科学基金:“双营养因子缓释型轴向取向纳米纤维神经导管诱导长距离神经再生的研究”

7.国家自然科学基金:“仿生活性丝素蛋白-P(LLA-CL)微纳米纱线针织支架用于兔跟腱再生”

8.国家高技术研究发展863计划纳米材料与器件专题:蛋白-多糖复合纳米纤维用于组织修复的研究

9.教育部归国留学人员基金:  纳米纤维的制备表征及在组织工程中的应用开发

10.上海市2005年重大基础研究课题子课题:  组织工程相关生物材料的基础科学问题研究中的小血管组织工程再建

11.上海市白玉兰科技人才基金:小口径血管组织再生的研究

12.上海市科委非政府国际合作项目:  控释型活性纳米纤维神经导管及心脏瓣膜的研制

13.上海市科纳米专项:纳米纤维仿生材料用于组织修复的研究

14.上海市科纳米专项:蛋白-多糖-PLLA-CL)复合纳米纤维用于小血管组织再生

15.上海市科委重点基础研究项目:“纳米纤维和纳米纱双层仿生血管支架及体内血管再生的研究”

16.上海市科委2015年科技支撑医疗器械项目:“活性纳米纤维神经导管的制备及体内神经再生的研究”

17.教育部博士点基金:“仿生活性纳米纤维神经导管诱导长距离神经再生的研究”

18.“纺织之光”应用基础研究项目 ,  “活性纳米纤维神经导管用于长距离神经修复的研究 

近三年发表的文章:

1.  Xuezhe Liu, Xi He, Dawei Jin, Shuting Wu, Hongsheng Wang, Meng Yin, Ali Aldalbahi, Mohamed El-Newehyc, Xiumei Mo*, Jinglei Wu*A biodegradable multifunctional nanofibrous membrane for periodontal tissue regenerationActa Biomaterialia 2020108207–222

2.  Tong Wu, Xiumei Mo, and Younan Xia*, Moving Electrospun Nanofibers and Bioprinted Scaffolds toward Translational Applications, Adv. Healthcare Mater. 2020, 1901761

3.  Jingjing Zhu, Dian Chen, Juan Du, Xinxin Chen, Jianhong Wang, Haibo Zhang, Sihao Chen, Jinglei Wu*, Tonghe Zhu*, and Xiumei Mo*, Mechanical matching nanofibrous vascular scaffold with effective anticoagulation for vascular tissue engineering, Composites Part B:, 2020, 186,107788

4.  Wenshuai Fan, Liu Yuan, Jinghuan Li, Zhe Wang, Jifei Chen, Changan Guo, Xiumei Mo*, Zuoqin Yan*Injectable double -crosslinked hydrogels with kartogenin -conjugated polyurethane nano -particles and transforming growth factor β3 for in -situ cartilage regenerationMaterials Science and Engineering: C2020, 110, 110705

5. Jia Liu, Jun Li, Fan Yu, Ya-xin Zhao, Xiu-mei Mo, Jian-feng PanIn situ forming hydrogel of natural polysaccharides through Schiff base reaction for soft tissue adhesive and hemostasisInternational Journal of Biological Macromolecules

6.Weiming Chen, Yong Xu, Yaqiang Li, Litao Jia, Xiumei Mo*, Gening Jiang*, Guangdong Zhou*, 3D printing electrospinning fiber-reinforced decellularized extracellular matrix for cartilage regeneration, Chemical Engineering Journal, 2020, 382, 122986

7. Linlin Ma, Xiaoyun Wang, Jinglei Wu, Dongdong Zhang, Lin Zhang, Xinran Song, Huoyan Hong, Chuanglong He, Xiumei Mo, Sufang Wu*, Guoyin Kai*, Hongsheng Wang*, Polyethylenimine and sodium cholate-modified ethosomes complex as multidrug carrier for the treatment of melanoma through transdermal deliveryNanomedicine 2019

8. Tong Wu, Haoxuan Li, Jiajia Xue, Xiumei Mo, and Younan Xia*Photothermal Welding, Melting, and Patterned Expansion of Nonwoven Mats of Polymer Nanofibers for Biomedical and Printing ApplicationsAngew. Chem. Int. Ed. 2019, 58, 16416 –16421

9.Tong Wu, Haoxuan Li, Minghao Xie, Song Shen, Wenxia Wang, Ming Zhao, Xiumei Mo, Younan Xia*, Incorporation of gold nanocages into electrospun nanofibers for efficient water evaporation through photothermal heating,Materials Today Energy 2019, 12, 129-135

10. Fei Yu, Runqing Fu, Lu Liu, Xiaoting Wang, Tingting Wu, Wei Shen, Zhipeng Gui, Xiumei Mo*, Bing Fang* and Lunguo Xia*Leptin-Induced Angiogenesis of EA.Hy926 Endothelial Cells via the Akt and Wnt Signaling Pathways In Vitro and In VivoFrontiers in Pharmacology, 2019,10,1275, doi: 10.3389/fphar.2019.01275

11. Atta ur Rehman Khan, Muhammad Nadeem, M. Aqeel Bhutto, Fan Yu, Xianrui Xie, Hany El-Hamshary, Ayman El-Faham, Usama A. Ibrahim and Xiumei Mo*Physico-Chemical and Biological Evaluation of PLCL/SF Nanofibers Loaded with Oregano Essential OilPharmaceutics 2019, 11, 386; doi:10.3390/pharmaceutics11080386

12.Xianrui Xie, Dongsheng Li, Changming Su, Wei Cong, Xiumei Mo, Guige Hou*, and Chunhua Wang*, Functionalized Biomimetic Composite Nanfibrous Scaffolds with Antibacterial and Hemostatic Efficacy for Facilitating Wound Healing, Journal of Biomedical Nanotechnology, 2019, 15, 1267–1279

13. Wei Zhai, Li-jun Qiu, Xiu-mei Mo, Sheng Wang, Yun-fei Xu, Bo Peng, Min Liu, Jun-hua Huang, Guang-chun Wang, Jun-hua Zheng*, Coaxial electrospinning of P(LLA-CL)/heparin biodegradable polymer nanofibers: potential vascular graft for substitution of femoral artery, J Biomed Mater Res Part B 2019: 107B: 471-478

14.Mingjun Du#, Jianmin Gu#Juan Wang, Yizheng Xue, Yiwen Ma, Xiumei Mo* and Song Xue*Silk fibroin/poly(L‑lactic acid‑co‑ε‑caprolactone) electrospun nanofibrous scaffolds exert a protective effect following myocardial infarctionExperimental and Therapeutic Medicine 2019, 17: 3989-3998

15. Weiming Chen, Yong Xu, Yanqun Liu, ZongxinWang, Yaqiang Li, Gening Jiang, Xiumei Mo*, Guangdong Zhou*, Three-dimensional printed electrospun fiber-based scaffold for cartilage regeneration, Materials and Design 2019, 179, 107886

16. Dawei Jin, Junfeng Hu, Dekai Xia, A’li Liu, Haizhu Kuang, Jun Du, Xiumei Mo*, Meng Yin*, Evaluation of a simple off-the-shelf bi-layered vascular scaffold based on poly(L-lactide-co-ε-caprolactone) /silk fibroin in vitro and in vivo, International Journal of Nanomedicine2019:14 4261–4276

17. Juan Wang, Wei Zheng, Liang Chen, Tonghe Zhu, Wei Shen, Cunyi Fan, Hongjun Wang, and Xiumei Mo*, Enhancement of Schwann Cells Function Using Graphene-OxideModified Nanofiber Scaffolds for Peripheral Nerve Regeneration, ACS Biomater. Sci. Eng. 2019, 55, 2444−2456

18. Kaiqiang Ye, Haizhu Kuang, Zhengwei You, Yosry Morsi and Xiumei Mo*Electrospun Nanofibers for Tissue Engineering with Drug Loading and ReleasePharmaceutics 2019, 11, 182; doi:10.3390/pharmaceutics11040182

19.Dongdong Zhang, Linpeng Fan, Linlin Ma, Junqiu Liu, Kai Zhou, Xinran Song, Meiqi Sun, Xiumei Mo, Chuanglong He, Yuxin Chen*, and Hongsheng Wang*, Helicobacter pylori Ribosomal Protein-A2 Peptide/Silk Fibroin Nanofibrous Composites as Potential Wound Dressing, J. Biomed. Nanotechnol.2019, 15(3), 507-517

20.Dinghua Liu, Wei Nie, Dejian Li, Weizhong Wang, Lixia Zheng, Jingtian Zhang, Jiulong Zhang, Chen Peng, Xiumei Mo, Chuanglong He*, 3D printed PCL/SrHA scaffold for enhanced bone regeneration, Chemical Engineering Journal 2019, 362, 269–279

21.Xiaojun Zhou, Qianqian Zhang, Liang Chen, Wei Nie, Weizhong Wang, Hongsheng Wang, Xiumei Mo, and Chuanglong He*, Versatile Nanocarrier Based on Functionalized Mesoporous Silica Nanoparticles to Codeliver Osteogenic Gene and Drug for Enhanced Osteodifferentiation, ACS Biomater. Sci. Eng. 2019, 5, 710−723

22. Dong Lei, Yang Yang, Zenghe Liu, Shuo Chen, Benyan Song, Ao Shen, Binqian Yang, Sen Li, Zhize Yuan, Quan Qi, Lijie Sun, Yifan Guo, Han Zuo, Shixing Huang, Qi Yang, Xiumei Mo, Chuanglong He, Bo Zhu, Eric M. Jeffries, Feng-Ling Qing, Xiaofeng Ye,* Qiang Zhao* and Zhengwei You *, A general strategy of 3D printing thermosets for diverse applications, Mater. Horiz., 2019, 6, 394-404

23.Dongsheng Li, Yonglin Gao, Yunzhi Wang, Xiaoping Yang, Chuanglong He, Meifang Zhu, Shumin Zhang and Xiumei Mo*Evaluation of biocompatibility and immunogenicity of micro/nanofiber materials based on tilapia skin collagenJournal of Biomaterials Applications, 2019, 3381118–1127

24. XuranGuo, JinjingZhu,HongmeiZhang,  ZhengweiYou,Yosory Mosi,Xiumei Mo*, Tonghe Zhu*, Facile preparation of a controlled-release tubular scaffold forblood vesselimplantation, JournalofColloid and InterfaceScience, 2019, 539, 351-360

25.Lijie Sun, Min Wang, Shuo Chen, Binbin Sun, Yifan Guo, Chuanglong He, Xiumei Mo, Bo Zhu, Zhengwei You*, Molecularly engineered metal-based bioactive soft materials – Neuroactive magnesium ion/polymer hybridsActa Biomaterialia 201985 310–319

26. Juan Wang, Yuan Cheng, Liang Chen, Tonghe Zhu, Kaiqiang Ye, Chao Jia, Hongjun Wang, Meifang Zhu, Cunyi Fan*, Xiumei Mo* , In vitro and in vivo studies of electroactive reduced graphene oxide-modified nanofiber scaffolds for peripheral nerve regenerationActa Biomaterialia 2019, 84, 98–113

27.Kaiqiang Ye, Dinghua Liu, Haizhu Kuang, Jiangyu Cai, Weiming Chen, Binbin Sun, Lunguo Xia, Bing Fang, Yosry Morsi, Xiumei Mo*Three-dimensional electrospun nanofibrous scaffolds displaying bone morphogenetic protein-2-derived peptides for the promotion of osteogenic differentiation of stem cells and bone regenerationJournal of Colloid and Interface Science 2019, 534, 625–636

28.Binbin Sun, Zifei Zhou, Dawei Li, Tong Wu, Hao Zheng, Junjian Liu, Gangyang Wang, Yinxian Yu* , Xiumei Mo*Polypyrrole-coated poly(l-lactic acid-co-ε-caprolactone)/silk fibroin nanofibrous nerve guidance conduit induced nerve regeneration in rat, Materials Science & Engineering C , 2019, 94 , 190–199

29. Haizhu Kuang, Shuofei Yang, Yao Wang, Yuting He, Kaiqiang Ye, Junfeng Hu, Wei Shen, Yosry Morsi, Shuyang Lu, and Xiumei Mo∗, Electrospun Bilayer Composite Vascular Graft with an Inner Layer Modified by Polyethylene Glycol and Haparin to Regenerate the Blood Vessel, J. Biomed. Nanotechnol. 2019, 151),77–84

30. 李丹丹,莫秀梅,基于席夫碱反应的氧化葡聚糖/胺化羧甲基壳聚糖双组分水凝胶粘合剂,中国组织工程研究,201822(22):3527-3532

31.  周恬,莫秀梅,孙皎,仿生鱼胶原复合膜引导牙周/ 骨组织再生的体外研究,口腔材料器械杂志,2018271,13-18

32.Peixi Liu, Yingjun Liu, Peiliang Li,Yingjie Zhou, Yaying Song, Yuan Shi, Wenhao Feng, Xiumei Mo, Hongyang Gao, Qingzhu An,*, and Wei Zhu*, Rosuvastatin- and Heparin-Loaded Poly(L‑lactide-co-caprolactone) Nanofiber Aneurysm Stent Promotes Endothelialization via Vascular Endothelial Growth Factor Type A Modulation, ACS Appl. Mater. Interfaces 2018, 10, 41012−41018

33.Yao Wang, Tonghe Zhu, Haizhu Kuang, Xiaoning Sun, Jingjing Zhu, Yu Shi,Chunsheng Wang, Xiumei Mo*, Shuyang Lu* and Tao Hong*, Preparation and evaluation of poly(ester-urethane) urea/gelatin nanofibers based on different crosslinking strategies for potential applications in vascular tissue engineering, RSC Adv., 2018, 8, 3591735927

34.Xin PAN, Binbin SUN*, and Xiumei MO*Electrospun polypyrrole-coated polycaprolactone nanoyarn nerve guidance conduits for nerve tissue engineeringFront. Mater. Sci. 2018, 12(4): 438–446

35.Shuo Chen, Tao Huang, Han Zuo, Sihao Qian, Yifan Guo, Lijie Sun, Dong Lei, Qilin Wu, Bo Zhu, Chuanglong He, Xiumei Mo, Eric Jeffries, Hao Yu, and Zhengwei You*, A Single Integrated 3D-Printing Process Customizes Elastic and Sustainable Triboelectric Nanogenerators for Wearable Electronics, Adv. Funct. Mater. 2018, 28, 180510

36. Weizhong Wang, Wei Nie, Dinghua Liu, Haibo Du, Xiaojun Zhou, Liang Chen, Hongsheng Wang, Xiumei Mo, lei li, Chuanglong He*, Macroporous nanofibrous vascular scaffold with improved biodegradability and smooth muscle cells infiltration prepared by dual phase separation technique, International Journal of Nanomedicine 2018:13 7003–7018

37. Hui Jing, Botao Gao, Manchen Gao, Haiyue Yin, Xiumei Mo, Xiaoyang Zhang, Kai Luo, Bei Feng, Wei Fu, Jing Wang, Wei Zhang, Meng Yin, Zhongqun Zhu, Xiaomin He* & Jinghao Zheng*, Restoring tracheal defects in a rabbit model with tissue engineered patches based on  TGF-β3-encapsulating electrospun poly(l-lactic acid-co-ε-caprolactone)/collagen scaffolds, ARTIFICIAL CELLS, NANOMEDICINE, AND BIOTECHNOLOGY, 2018, https://doi.org/10.1080/21691401.2018.1439844

38. Jing Wang, Lingling Tian, Nuan Chen, Seeram Ramakrishnab, Xiumei Mo*, The cellular response of nerve cells on poly-L-lysine coated PLGA-MWCNTs aligned nanofibers under electrical stimulation, Materials Science & Engineering C, 2018, 91, 715-726

39. Linlin Ma, Dongdong Zhang, Xingxing Yang, Lin Zhang, Jin Chu, Guoyin Kai*, Chuanglong He, Xiumei Mo and Hongsheng Wang*, Cirsium Japonicum DC ingredients-loaded silk fibroin nanofibrous matrices with excellent hemostatic activity, Biomed. Phys. Eng. Express 2018, 4, 025035

40. Jiangyu Cai, Juan Wang, Kaiqiang Ye, Dandan Li, Chengchong Ai, Dandan Sheng, Wenhe Jin, Xingwang Liu, Yunlong Zhi, Jia Jiang, Jun Chen, Xiumei Mo*, Shiyi Chen,Dual-layer aligned-random nanofibrous scaffolds for improving gradient microstructure of tendon-to-bone healing in a rabbit extra-articular model, International Journal of Nanomedicine 2018:13 3481–3492

41.Tong Wu, Jialing Zhang, Yuanfei Wang, Binbin Sun, Meng Yin, Gary L. Bowlin, and Xiumei Mo*, Design and Fabrication of a Biomimetic Vascular Scaold Promoting in Situ Endothelialization and Tunica Media Regeneration, ACS Appl. Bio Mater. 2018, 1, 833−844

42.Atta ur Rehman Khan, Shi Xiangyang, Aftab Ahmad and Xiu-mei Mo*Electrospinning of Crude Plant Extracts for Antibacterial and Wound Healing Applications: A ReviewSM Journal of Biomedical Engineering2018; 4(1): 1024

43. Kaile Zhang, Nailong Cao, Xuran Guo, Qingsong Zou, Shukui Zhou, Ranxing Yang, Weixin Zhao, Xiumei Mo, Wei Liu, Qiang Fu*, The fabrication of 3D surface scaffold of collagen/poly (L-lactide-co-caprolactone) with dynamic liquid system and its application in urinary incontinence treatment as tissue engineered sub-urethral sling:In vitro and in vivostudy, NeurourologyandUrodynamics.2018;37:978985.

44. Weiming Chen, Hany El-Hamshary, Salem S. AL-Deyab, Xiumei Mo*, A method to control curcumin release from PELA fiber by heat treatment, Advances in Polymer Technology, 2018, 37(3), 21705

45. Wenshuai Fan, Jinghuan Li, Liu Yuan, Jifei Chen, Zhe Wang, Yiming Wang, Changan Guo, Xiumei Mo, and Zuoqin Yan*, Intra-articular injection of kartogenin-conjugated polyurethane nanoparticles attenuates the progression of osteoarthritis, DRUG DELIVERY, 2018, 25(1), 1004–1012, https://doi.org/10.1080/10717544.2018.1461279

46. Haizhu Kuang, Yao Wang, Junfeng Hu, Chunsheng Wang, Shuyang Lu, Xiumei Mo*, A method for preparation of an internal layer of artificial vascular graft Co-modified with salvianolic acid B and heparin, ACS Applied Materials & Interfaces, 2018, 10(23), 19365-19372

47. Jing Wang, Lingling Tian, Liumin He, Nuan Chen, Seeram Ramakrishna, Kwok-Fai So, Xiumei Mo*, Lycium barbarum polysaccharide encapsulated Poly lactic-co-glycolic acid Nanofbers: cost efective herbal medicine for potential application in peripheral nerve tissue engineeringScientific Reports, (2018) 8:8669, DOI:10.1038/s41598-018-26837-Z

48. Jing Wang, Lingling Tian, Baiwen Luo, Seeram Ramakrishna, Dan Kai*, Xian Jun Loh, In Hong Yang, G. Roshan Deen, Xiumei Mo*Engineering PCL/Lignin Nanofibers as an Antioxidant Scaffold for the Growth of Neuron and Schwann cellColloids and Surfaces B: Biointerfaces2018, 169, 356-365

49. Jun Ma, Yunfei He, Xilin Liu, Weiming Chen, An Wang, Chia-Ying Lin, Xiumei Mo*, Xiaojian Ye*,Anovel electrospun-aligned nanoyarn/three-dimensional porous nanofibrous hybrid scaffold for annulus fibrosus tissue engineering, International Journal of Nanomedicine, 2018:13 1553–1567

50. Wencheng Liang, Jia Hou, Xiangchen Fang, Fudong Bai, Tonghe Zhu, Feifei Gao, Chao Wei, Xiumei Mo, Meidong Lang*, Syntheses of cellulose diacetate based copolymer electrospun nanofibers for tissue scaffold, Applied surface Science, 2018, 443, 374-381

51. Tong Wu, Jiajia Xue, Haoxuan Li, Chunlei Zhu, Xiumei Mo, and Younan Xia*, General Method for Generating Circular Gradients of Active Proteins on Nanofiber Scaffolds Sought for Wound Closure and Related Applications, ACS Applied Materials & Interfaces, 2018, 10, 85368545

52. Xiaojun Zhou, Weizong Weng, Bo Chen, Wei Feng, Weizhong Wang, Wei Nie, Liang Chen, Xiumei Mo, Jiacan Su *, Chuanglong He *, Mesoporous silica nanoparticles/gelatin porous composite scaffolds with localized and sustained release of vancomycin for treatment of infected bone defects, Journal of Materials Chemistry B, 2018,6,740-752

53. Liu YUAN, Wenshuai FAN, Linyingjun HAN, Changan GUO, Zuoqin YAN, Meifang ZHU, and Xiumei MO*Evaluation of hydrogels for soft tissue adhesives in vitro and in vivo analysesFront. Mater. Sci. 2018, 12(1): 95104

54. Tong Wu, Jialing Zhang, Yuanfei Wang, Dandan Li, Binbin Sun, Hany El-Hamshary, Meng Yin*, Xiumei Mo*Fabrication and preliminary study of a biomimetic tri-layer tubular graft based on fibers and fiber yarns for vascular tissue engineeringMaterials Science & Engineering C201882, 121–129

55.Zhiwen Zeng, Hongsheng Wang, Yosry Morsi, Xiumei Mo*, Synthesis and characterization of incorporating mussel mimetic moieties into photoactive hydrogel adhesive, Colloids and Surfaces B: Biointerfaces, 2018, 161, 94–102

56. Ziqi Gu, Haiyue Yin, Juan Wang, Linlin Ma, Yosry Morsi, Xiumei Mo*, Fabrication and characterization of TGF-1-loaded electrospun poly (lactic-co-glycolic acid) core-sheath sutures,Colloids and Surfaces B: Biointerfaces 2018, 161, 331–338

57. Jing Wang, Nuan Chen, Seeram Ramakrishna, Lingling Tian,* and Xiumei Mo*,The Effect of Plasma Treated PLGA/MWCNTs-COOH Composite Nanofibers on Nerve Cell Behavior, Polymer 2017, 9, 713

58. Kui Yu, Xiangxiang Zhou, EI-Assar M R, Tonghe Zhu, Yu Wu, Juang Wang, Wenhao Feng, Yosry Morsi, Xiumei MO*, Preparation and Characterization of Chitosan Nanofibers Containing Silver Nanoparticles, Journal of Donghua University (Eng. Ed.) , 2017,34(1) 105-110

59. Xiaojun Zhou, Ming Qin, Liang Chen, Wei Nie, Xiumei Mo, Chuanglong He*, Effect of Polyethlenimine Content on Liposome/Polyethylenimine Complexes Mediated Gene Delivery, Journal of Donghua University (Eng. Ed.) , 2017, 34(2) 195-198

60. Fengjuan Zou, Runrun Lia, Jianjun Jiang, Xiumei Mo, Guofeng Gu, Zhongwu Guo and Zonggang Chen*Mechanical enhancement and in vitro biocompatibility of nanofibrous collagen-chitosan scaffolds for tissue engineeringJournal of Biomaterials Science, Polymer Edition, 201728(18), 2255–2270

61. Anlin Yin, Jiukai Li, Xiumei Mo, Rifang Luo, Xingdong Zhang, Yunbing Wang⁎, Fabrication and characteration of coaxial electrospun multicomponent fibrous graft for vascular tissue engineering, Journal of Controlled Release, 2017, 259, e5e195

62. Tong Wu, Binbin Sun, Dandan Li, Xiumei Mo*Anti-CD133 antibody loaded bilayer tubular scaffold based on poly(L-lactide-co-caprolactone)/collagen nanofibers and nanoyarns for vascular tissue engineering, Journal of Controlled Release, 2017, 259, e5e195

63.Linpeng Fan, Zengxiao Cai, Xiaohua Geng, Hongsheng Wang, Jingliang Li, Chuanglong He, Xiumei Mo, Xungai Wang, Fabrication and characterization of compound vitamin B/silk fibroin nanofibrous matrices, Journal of Controlled Release 2017, 259, e5–e195

64. Chongyang Wang, Wenxiu Hou, Xuran Guo, Juehong Li, Tu Hu, Manle Qiu, Shen Liu, Xiumei Mo⁎, Xudong Liu⁎, Two-phase electrospinning to incorporate growth factors loaded chitosan nanoparticles into electrospun fibrous scaffolds for bioactivity retention and cartilage regeneration, Materials Science and Engineering C, 2017,79, 507–515

65. Tian Zhou, Xin Liu, Baiyan Sui, Chao Liu, Xiumei Mo* and Jiao Sun*, Development of fish collagen/bioactive glass/chitosan composite nanofibers as a GTR/GBR membrane for inducing periodontal tissue regeneration, Biomed. Mater. 2017, 12, 055004

66. Zhiwen Zeng, Xiumei Mo*, Rapid in situ cross-linking of hydrogel adhesives based on thiol-grafted bioinspired catechol-conjugated chitosan, Journal of Biomaterials Applications 2017, 32(5), 612–621

67. Kaile Zhang, Nailong Cao, Xuran Guo, Qingsong Zou, Shukui Zhou, Ranxing Yang, Weixin Zhao, Xiumei Mo, Wei Liu, Qiang Fu*, The fabrication of 3D surface scaffold of collagen/poly(L-lactide-co-caprolactone) with dynamic liquid system and its application in urinary incontinence treatment as a tissue engineered sub-urethral sling: In vitro and in vivo study, Neurourology and Urodynamics, 2017, 1-8

68. Juan WANG, Binbin SUN, Muhammad Aqeel BHUTTO, Tonghe ZHU, Kui YU, Jiayu BAO, Yosry MORSI, Hany EL-HAMSHARY, Mohamed EL-NEWEHY, and Xiumei MO*Fabrication and characterization of Antheraea pernyi silk broin-blended P(LLA-CL) nanobrous scaffolds for peripheral nerve tissue engineering, Front. Mater. Sci. 2017, 11(1): 22–32

69. Abdalla Abdal-hay, Adnan Memic, Kamal H. Hussein, Yi Seul Oh, Mohamed Fouad, Fawzi F. Al-Jassir, Heung-Myong Woo, Yosry Morsi, Xiumei Mo, Sašo Ivanovski*, Rapid fabrication of highly porous and biocompatible composite textile tubular scaffold for vascular tissue engineering, European Polymer Journal, 2017, 96, 27-43

70. Yu WU, Liu YUAN, Nai-an SHENG, Zi-qi GU, Wen-hao FENG, Hai-yue YIN, Yosry MORSI, and Xiu-mei MO*A soft tissue adhesive based on aldehyde-sodium alginate and amino-carboxymethyl chitosan preparation through the Schiff reactionFront. Mater. Sci. 2017, 11(3): 215–222

71. Wenhao Feng, Peixi Liu, Haiyue Yin, Ziqi Gu, Yu Wu, Wei Zhu, Yingjun Liu, Hao Zheng and Xiumei MO*,Heparin and rosuvastatin calcium-loaded poly-( L -lactide-co-caprolactone) nanofiber-covered stent-grafts for aneurysm treatment,New J.Chem., 2017, 41, 9014-9023, impact factor 3.269

72. Haiyue Yin, Juan Wang, Ziqi Gu, Wenhao Feng, Manchen Gao, Yu Wu, Hao Zheng, Xiaomin He and Xiumei Mo*,Evaluation of the potential of kartogenin encapsulated poly(L-lactic acid-co-caprolactone)/collagen nanofibers for tracheal cartilage regeneration,Journal of Biomaterials Applications, 2017, 32(3) , 331–341, imnpact factor 2.3

73.  Binbin Sun, Zifei Zhou, Tong Wu, Weiming Chen, Dawei Li, Hao Zheng, Hany El-Hamshary, Salem S. Al-Deyab4, Xiumei Mo*, Yinxian Yu*, Development of Nanofiber Sponges-Containing Nerve Guidance Conduit for Peripheral Nerve Regeneration in Vivo, ACS Applied Materials & Interfaces, 2017, 9, 2668426696

74. PiJun Yu, JiAn Guo, JunJie Li, Xiao Shi, LuPing Wang, Wei Chen, and XiuMei MoRepair of Skin Defects with Electrospun Collagen/Chitosan and Fibroin/Chitosan Compound Nanofiber Scaffolds Compared with Gauze Dressing,Journal of Biomaterials and Tissue Engineering, 2017, 7(5), 386-392

75.Yinxian YU, Binbin SUN, Chengqing YI, and Xiumei MO*,Stem cell homing-based tissue engineering usingbioactive materials, Front. Mater. Sci. 2017, 11(2): 93105

76. Jing Wang, Binbin Sun, Lingling Tian, Xiaomin He, Qiang Gao, Tong Wu, Seeram Ramakrishna, Jinghao Zheng, Xiumei Mo*, Evaluation of the potential of rhTGF- β3 encapsulated P(LLA-CL)/collagen nanofibers for tracheal cartilage regeneration using mesenchymal stems cells derived from Wharton's jelly of human umbilical cord, Materials Science and Engineering C 70 (2017) 637–645

77. Bensong Han, Feng Xue, Cunyi Fan and Xiumei Mo, Surface heparinization and blood compatibility modification of small intestinal submucosa (SIS) for small-caliber vascular regeneration, Bio-Medical Materials and Engineering 2017, 28, 213–222

78. Liu Yuan, Yu Wu, Jun Fang, Xiaojuan Wei, Qisheng Gu, Hany El-Hamshary, Salem S. Al-Deyab, Yosry Morsi & Xiumei Mo*, Modified alginate and gelatin cross-linked hydrogels for soft tissue adhesive, Artificial Cells, Nanomedicine, and Biotechnology An International Journal, 2017, 45(1),76-83, impact factor 5.605

79. Liu Yuan, Yu Wu, Qi-sheng Gu, Hany El-Hamshary, Mohamed El-Newehy, Xiumei Mo, Injectable photo crosslinked enhanced double-network hydrogels from modified sodium alginate and gelatin, International Journal of Biological Macromolecules, 2017, 96, 569–577

80. Kaile Zhang, Qiang Fu, James Yoo, Xiangxian Chen, Prafulla Chandra, Xiumei Mo, Lujie Song, Anthony Atala, Weixin Zhao*, 3D bioprinting of urethra with PCL/PLCL blend and dual autologous cells in fibrin hydrogel: An in vitro evaluation of biomimetic mechanical property and cell growth environment, Acta Biomaterialia 2017, 50, 154–164

81. Yibo Gan, Pei Li, Liyuan Wang, Xiumei Mo, Lei Song, Yuan Xu, Chen Zhao, Bin Ouyang, Bing Tu, Lei Luo, Linyong Zhu, Shiwu Dong, Fuyou Li, Qiang Zhou*, An interpenetrating network-strengthened and toughened hydrogel that supports cell-based nucleus pulposus regeneration, Biomaterials 2017, 136 , 12-28

82. Tonghe Zhu, Kui Yu, M. Aqeel Bhutto, Xuran Guo, Wei Shen, Juan Wang, Weiming Chen, Hany El-Hamshary, Salem S. Al-Deyab, Xiumei Mo*Synthesis of RGD-peptide modified poly(ester-urethane) urea electrospun nanofibers as a potential application for vascular tissue engineering, Chemical Engineering Journal 2017, 315, 177–190, Impact factor 6.1206

83. Tong Wu, Jialing Zhang, Yuanfei Wang, Binbin Sun, Xuran Guo, Yosry Morsi, Hany El-Hamshary, Mohamed El-Newehy, and Xiumei Mo*, Development of Dynamic Liquid and Conjugated Electrospun Poly(L-lactide-co-caprolactone)/Collagen Nanoyarns for Regulating Vascular Smooth Muscle Cells Growth, Journal of Biomedical Nanotechnology, 2017, 13, 303–312

84.Tian Zhou, Baiyan Sui, Xiumei Mo*, Jiao Sun*, Multifunctional and biomimetic fish collagen/bioactive glass nanofibers: fabrication, antibacterial activity and inducing skin regeneration in vitro and in vivo, International Journal of Nanomedicine 2017:12 3495–3507

85.Tong Wu, Dandan Li,Yuanfei Wang,Binbin Sun,Dawei Li,Yosry Morsi, Hany El-Hamshary,Salem S. Al-Deyaband Xiumei Mo*, Laminin-coated nerve guidance conduits based on poly(L-lactide-co-glycolide) fibers and yarns for promoting Schwann cells’ proliferation and Migration, J. Mater. Chem. B,2017, 5, 3186—3194

86. Weiming Chen, Binbin Sun, Tonghe Zhu, Qiang Gao, Yosry Morsi, Hany El-Hamshary,Mohamed El-Newehy, Xiumei Mo*, Groove fibers based porous scaffold for cartilage tissue engineering application, Materials Letters 2017, 192, 44–47

87. Anlin Yin*, Rifang Luo, Jiukai Li, Xiumei Mo*, Yunbing Wang*, Xingdong Zhang,Coaxial electrospinning multicomponent functional controlled-release vascular graft: Optimization of graft propertiesColloids and Surfaces B: Biointerfaces 2017, 152, 432–439

88. Kui Yu, Tonghe Zhu,Yu Wu, Xiangxiang Zhou, Xingxing Yang, Juan Wang, Jun Fang, Hany El-Hamshary, Salem S. Al-Deyab, Xiumei Mo*, Incorporation of amoxicillin-loaded organic montmorillonite into poly(ester-urethane) urea nanofibers as a functional tissue engineering scaffold, Colloids and Surfaces B: Biointerfaces, 2017, 151,314–323

89.Tong Wu,Hui Zheng,Jianfeng Chen,Yuanfei Wang,Binbin Sun,Yosry Morsi,Hany El-Hamshary,Salem S. Al-Deyab,Chang Chen*and Xiumei Mo*Application of a bilayer tubular scaffold based on electrospun poly(L-lactide-co-caprolactone)/collagen fibers and yarns for tracheal tissue engineering, Journal of Materials Chemistry B, 2017, 5,139-150

主要学术任职

1.中国生物材料学会理事

2.中国生物材料学会心血管材料分会委员

3.中国生物材料学会海洋生物材料分会理事

4.中国生物医学工程学会生物材料分会理事

5.中国复合材料学会超细纤维复合材料分会副主任委员

6.中国复合材料学生物医用复合材料分会委员

7.上海市生物医学工程学会理事

8.中国医药卫生文化协会生物医学材料专委会委员

9.Springer  的国际新刊物  “Frontiers  of  Materials  Science”  的编委

国际交流与合作:

目前与新加坡国立大学(National  University  of  Singapore),美国孟菲斯大学(UniversityofMemphis),澳大利亚斯文伯恩技术大学(Swinburne  University  of  Technology),澳大利亚迪肯大学(Deakin  University ,沙特国王大学(King  Saud  University) ,英国伦敦学院大学(UCL)有合作科研和教学 ,

联系电话:021-67792653                                                                                       EMAILxmm@dhu.edu.cn